JoNova

A science presenter, writer, speaker & former TV host; author of The Skeptic's Handbook (over 200,000 copies distributed & available in 15 languages).


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A cloud of Covid variants circles the globe

Mutations of SARS2 are roaming. Currently there are 19 million active (known) cases of Covid. Due to copying errors, mistakes are accumulating in the genes of the virus. It’s a relentless process of trial and selection. A trillion monkeys on keyboards blindly working its way around vaccines, and immune systems. To beat this, we need to understand it.

Below is a map of known variants created from the samples which have had full sequences done. This is the remarkable “Nextstrain“ — an opensource tool. I have labelled a few clusters by their “country names”, (though we’re not supposed to do that. Let’s all say “WuFlu”.)

The family tree of SARS-Cov-2 starts at the bottom left corner with two samples from Wuhan around Christmas 2019. This is called the 19A clade, which appears to have almost died out now, though there are still remnants left of this original virus in corners like Iran and PNG. Otherwise, the Wuhan 19A virus has been superseded by its children.

The branches and time marches to the right.

Nextstrain: Latest global SARS-CoV-2 analysis

The code for one full virus is 29,000 bases long and as best as I can tell, all the dots […]

China took Manufacturing, then Tech and the West gave them away. Now it’s come for biotech…

China has become the Wild West of bio-research

 

The ZMan spots a repeat cycle of knowledge-hauls as China siphons off Western intellectual property, often with the help of the West.

First China hauled (and we gave) the factories, then it was the hi tech industry, now it’s biomedical ingenuity. The pattern repeats. China offered cheap labor for manufacturers and the tech industry with few annoying environmental burdens. Now China offers money and freedom from ethical quandaries for researchers who want to clone, create bioweapons, or hybrid human-animal cells.

The question for the West is, if environmental or ethical standards matter at home, shouldn’t they matter overseas too? If we aren’t happy to buy shirts made by slaves at home, why are foreign slave shirts OK? If we aren’t keen to fund bioweapons research in our own lands, why was it OK to help do that in China? (Thank Anthony Fauci).

Chinese Ethics, The ZMan

China makes it so easy for Western Scientists to collaborate:

There is no doubt that most Western governments operate biological research facilities. The fact that China is doing the same is no surprise. The difference is Western governments have to […]

Paralyzed mice walk again after just a few weeks

We all could use some good news, and this is quite extraordinary.

“Using gene therapy, a research team has succeeded in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.”

The Town Mouse and The Country Mouse both like this news. | Illustrated by Milo Winter

Normally spinal cord damage is pretty much permanent. Even though we all still have the same genes that built the nerves in the first place, no one seemed to have the right reboot code that could switch on the correct genes in the right order to do the repair. And to give you some idea of the complexity of this, in 2018 a different team estimated that as many as 580 genes may be involved in axon regeneration.

Plenty of researchers have been tapping on the windows and doors of the Nerve Regrowth Holy Grail. This time, instead of just regenerating a nerve in a petri dish, or even even a live animal, they’ve gone a leap further. These mice could walk again.

And all it took was a single injection? “This was a great surprise to the researchers”.

Dr. Li-Meng Yan claims The virus is man-made and spread to make damage

Dr Li-Meng Yan worked in the WHO Coronavirus Reference Lab in Hong Kong. She has just published a detailed paper claiming that the SARS-2 coronavirus was artificially made in a laboratory and appeared on Tucker Carlson’s show today. She also claims it was deliberately spread (though this was slightly ambiguous– listen closely).

We already had enough evidence to know that SARS-Cov2 is a likely bioweapon. (The virus it supposedly evolved from appears to be fake.) This is largely what her paper covers.

Chinese defector virologist Dr Li-Meng Yan publishes report claiming COVID-19 was made in a lab

Phoebe Looms, News.com

Dr Yan had been working at Hong Kong University’s public health laboratory sciences division, a World Health Organisation infectious diseases research centre, when her boss was asked to investigate the outbreak in Wuhan.

Dr Yan claimed her and her team’s scientific findings were suppressed, and they were told only to report cases linked to the Huanan seafood market. After becoming fearful of her safety, she fled China on a flight bound for Los Angeles in late April.

Others in her lab said: “ Dr. Yan’s statement does not accord with the key facts […]

Reinfection and T cell immunity — does the common cold give us protection against Coronavirus?

The first case of a definitive reinfection was reported today

Before we look at whether a cold gives us protection let’s point out we don’t know how well a SARS 2 infection gives us protection.

A 33 year old man in Hong Kong was tested positive nearly five months after his first infection, and with a slightly different variant of the virus, so it’s very likely this was a second infection rather than a resurgence of the first. It hints that Covid may be a bit like the common cold, and our immunity may be partial and temporary which is not good news for the herd immunity idea and the vaccine plan, but it’s only one case. On the plus side, he had a three day fever, cough and sickness in March, but is asymptomatic this time, suggesting that maybe there is enough residual immunity to help him beat the second infection.

There have been other reports of people getting reinfected but none of the previous cases had genetic testing of both infections to show they were different. But 13% of 4,000 doctors who were surveyed in May (even at that early stage) believed that at least one of their […]

Evidence grows that Coronavirus was man-made: the bat virus it “evolved” from appears to be faked

The claims that the current pandemic Coronavirus is natural all rely on it being 96% closely related to a natural bat virus known as the RaTG13 virus. But new analysis suggests this “natural” virus only exists as a fake creation on a Chinese computer.

The implications of this type of work will affect global politics. The anger towards the Chinese CCP mismanagement, dishonesty, and the coverup will unite the world against the global bad-citizen player. It also drives a pike through the casual globalist academic programs, and the role of people like Anthony Fauci, chief advisor to Trump, head of the Expert Swamp in the US. Why was he sending money to the Wuhan Institute of Virology? Why did the West help train and supply this lab?

h/t ramblingidiot, Choroin, Selwyn, El Gordo, Rob Dinn, Mike Mitchell

The virus that SARS-CoV-2 is supposed to have evolved from looks unmistakably artificial — in sections it contains far too many “mutations” that matter but hardly any of the normal noise of silent mutations which always occur naturally alongside the mutations which change the end product. Like someone cut and pasted multiple photos together with different background noise. Other sections of the […]

Adapting to climate change “it’s in our genes” — Another reason to ignore the extinction scare

Two different models predict two totally different futures. On the left, catastrophic extinction. On the right, happy bats. Click to enlarge

Yesterday a UN supercommittee of 145 scientists from 50 countries declared that one million species are set for extinction. The same day, ten other scientists published a paper pointing out that most modelers forget to allow for genetic variation and thus overestimate the extinction rate. (It’s like they’re modelling the World of Clones – take one small study, pretend they’re all the same — extrapolate globally.) Have a look at the big difference in model outcomes in figure 1 (right).

As I keep saying, 500 million years of brutal climate change means almost every species carries around an industrial tool-kit of handy genetic tricks. Matz et al estimated corals already have the genes to survived another 250 years of projected IPCC catastrophe (in the unlikely event that it happens). Liew et al showed corals even have epigenetic tricks as well as genetics ones. Another group showed when corals are heated something like 74 different genes are activated — often genes that we don’t even know what they’re there for.

My favourite all time Global Adaptability Prize goes to […]

Scientist create, then cure, baldness, wrinkles and some aging in mice

Here’s a tantalizing bit of gene research. Scientists were able to switch off a central gene in the nucleus of a mouse cell. That in turn meant the mouse’s mitochondria started failing (I’m going to be talking a lot more about these fascinating bits of machinery in our cells). After two months, the poor lab mice were wrinkled, going bald and their organs were aging rapidly, but lo, after the gene in the nucleus was switched on again, the mitochondria were restored, and wow, all the hair and skin grew back to what it had been before.

Mitochondria have their own DNA loops.

Why get excited about mitochondria? These are tiny biological batteries we have inside every cell. The are the mini-factories burning sugar or fat, generating free radicals on a mass scale and churning out the chemical energy that is then used in most of the chemical reactions in our body. They are turning up in every second paper these days related to aging. These little organelles are so important and rule breaking they even have their own DNA loops with 37 genes — this is the only genetic material in us that is not part of the […]

Corals use epigenetic tricks to adapt to warmer and “more acidic” water

After half a billion million years of climate change, I’m shocked, shocked I tell you, that life on Earth (and specifically corals) have so many ways to cope with the climate changing. After all, it’s natural (if you are trained by Greenpeace) to assume that corals can only survive in a world with one constant stable temperature just like they never had.

One more tool in the coral-reef-workshop

Corals don’t just have a tool-box, they have a Home Depot Warehouse. h/t to GWPF

We already knew corals chuck out the symbionts that don’t work so well and pick up better partners. Plus, evolution left a stack of genes lying around that were honed in a world that was warmer, and natural selection has a way of amplifying better combinations as conditions shift. Then there is the way corals can be reseeded from safe sites, far away. Now we find out that corals can use epigenetics too.

Epigenetics is that kind of spooky effect where people can inherit the exact same DNA code yet it works or doesn’t work depending on whether it was Dad’s copy, or Mum’s, or whether parents were starved, fearful or stressed. It’s weird, see […]

Life adapts — fish evolved from salt to fresh water in just fifty years

In 1964 an earthquake made some parts of the Pacific into ponds on a few islands. Fifty years later and the fish in those ponds are now freshwater fish. Apparently the genes for dealing with that sort of wild extreme change are held by some of the fish in the crowd and natural selection can work its wonders in a decade.

In terms of ocean acidification, this is as catastrophic as it gets, not only did the ocean become “more acidic” but it stopped being an ocean.

It can’t get much worse than this for a fish, and yet somehow life on Earth had the answer.

What’s the pH of those ponds — The ocean pH is 8.1, rain is 5.5. Those ponds will be somewhere in between.

And some people think a man-made “ocean acidication” that’s smaller than this and slower, will devastate the ocean.

 

Science Daily

Evolution is usually thought of as occurring over long time periods, but it also can happen quickly. Consider a tiny fish whose transformation after the 1964 Alaskan earthquake was uncovered by University of Oregon scientists and their University of Alaska collaborators.

The fish, […]